ITP is a rare, often chronic bleeding disorder where reduced numbers of platelets (cells that stop or prevent bleeding) can lead to an increased risk of bleeding and bruising, and an impaired quality of life, especially due to severe fatigue and fear about the condition.
ITP occurs when the immune system produces IgG antibodies that destroy platelets and reduce platelet production. In primary ITP, the trigger of the autoimmune response is not known. There is another form of ITP, called secondary ITP, which results from another underlying condition.